Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.44 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7678157 | 1.00 | KCNN4 (0.46) | KCNN4KCNA3AVPR2AVPR1ACYP2C19 | |
| SCHEMBL16639239 | 0.87 | MAPT (0.41) | CYP2C19MAPTCYP2C9LMNAGAA | |
| SCHEMBL18926571 | 0.87 | MAPT (0.41) | CYP2C19MAPTCYP2C9LMNAGAA | |
| SCHEMBL7682770 | 0.86 | KCNN4 (0.42) | KCNN4KCNA3AVPR2AVPR1ACYP2C19 | |
| SCHEMBL7682776 | 0.86 | KCNN4 (0.42) | KCNN4KCNA3AVPR2AVPR1ACYP2C19 | |
| SCHEMBL8672389 | 0.81 | KCNN4 (0.60) | KCNN4KCNA3CYP2C19MAPTCYP3A4 | |
| SCHEMBL16628529 | 0.78 | LMNA (0.39) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL16628531 | 0.78 | LMNA (0.39) | MAPTLMNAGAAMEN1KMT2A | |
| SCHEMBL6605034 | 0.77 | KMT2A (0.51) | KCNN4KCNA3MAPTLMNANPSR1 | |
| SCHEMBL6605044 | 0.77 | KMT2A (0.51) | KCNN4KCNA3MAPTLMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340678-B1 | FOR THERAPY OF THREATENED PREMATURE BIRTH OR ABORTION, DYSMENORRHEA, CONTRACTION OF UTERINE SMOOTH MUSCLE, RELEASE OF MILK, ENDOMETRIOSIS, NEED FOR FEEDING CONTROL, DISTURBANCE OF MEMORY, NATRIURESIS, NEED FOR CARBOHYDRATE METABOLISM | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 2002-01-22 | — | — | US | disclosed |
| EP-0987264-A1 | 4,4-DIFLUORO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPINE DERIVATIVES AND DRUG COMPOSITIONS CONTAINING THEM | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 2000-03-22 | — | — | EP | disclosed |