SCHEMBL7678258

SCHEMBL7678258

c1cc2cc3ccc3cc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 8/20 0.50
CYP1A2 P05177 6/20 0.50
ALDH1A1 P00352 5/20 0.44
CYP3A4 P08684 4/20 0.44
HSD17B10 Q99714 4/20 0.44
TDP1 Q9NUW8 3/20 0.44
ALOX15 P16050 2/20 0.44
HIF1A Q16665 2/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
HBB P68871 1/20 0.44
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
ACHE P22303 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
F2 P00734 1/20 0.37
LMNA P02545 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL28040711 0.94 CYP2A6 (0.47) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Naphthalene SCHEMBL2263115 0.82 CYP2A6 (0.67) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Dimethylamine SCHEMBL28410171 0.82 CYP2A6 (0.47) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL5713429 0.78 CYP2A6 (0.64) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL29352043 0.78 CYP2A6 (0.64) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL2833889 0.78 CYP2A6 (0.64) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL7703 0.78 CYP2A6 (0.64) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL23302274 0.75 CYP2A6 (0.58) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL7621971 0.75 CYP2A6 (0.58) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL12988658 0.75 CYP2A6 (0.58) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6500363-B1 CHARGED AROMATIC DONOR/ACCEPTOR MOIETIES WITH MOLECULAR POLYHEDRAL AND PI-DELOCALIZED-BASED SYSTEMS PROVIDES COMPOUNDS WITH EXCEPTIONAL NLO RESPONSES; BORON CAGE COMPOUNDS SYRACUSE UNIVERSITY 2002-12-31 US claimed
WO-2001000631-A1 NEW CLASSES OF HIGH LINEAR AND NONLINEAR RESPONSE COMPOUNDS NANOWORKS, INC. (US) 2001-01-04 WO claimed
US-5770763-A POLYARYLCYCLOBUTENES DERIVED FROM 3,6 FUNCTIONALIZED MONO AND DICYCLOBUTABENZENE THE BOARD OF REGENTS OF THE UNIV. OF MICHIGAN (US) 1998-06-23 US disclosed
US-5552508-A Difunctional bitricyclodecatriene monomers UNIVERSITY OF MICHIGAN, THE BOARD OF REGENTS (US) 1996-09-03 US disclosed
US-4719283-A Preparation of polyimide from bis-imide and benzocyclobutene HUELS AKTIENGESELLSCHAFT (DE) 1988-01-12 US disclosed