Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL28040711

N.c1cc2cc3ccc2cc13

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 7/20 0.47
CYP1A2 P05177 6/20 0.47
ALDH1A1 P00352 5/20 0.42
CYP3A4 P08684 4/20 0.42
HSD17B10 Q99714 4/20 0.42
TDP1 Q9NUW8 3/20 0.42
ALOX15 P16050 2/20 0.42
HIF1A Q16665 2/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
HBB P68871 1/20 0.42
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
MEN1 O00255 2/20 0.35
ACHE P22303 2/20 0.35
KMT2A Q03164 2/20 0.35
F2 P00734 1/20 0.35
LMNA P02545 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7678258 0.94 CYP2A6 (0.50) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL29572399 0.80 CYP2A6 (0.58) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL3790663 0.80 CYP2A6 (0.58) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Ammonia Solution, Strong SCHEMBL15939955 0.77 ALDH1A1 (0.58) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Dimethylamine SCHEMBL28410171 0.77 CYP2A6 (0.47) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL27958925 0.77 CYP2A6 (0.54) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Naphthalene SCHEMBL2263115 0.77 CYP2A6 (0.67) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Phenanthrene SCHEMBL11570724 0.75 ALDH1A1 (0.75) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL29352043 0.74 CYP2A6 (0.64) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10
Anthracene SCHEMBL7703 0.74 CYP2A6 (0.64) CYP2A6CYP1A2ALDH1A1CYP3A4HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105037167-A Synthetic method of N, N-diaryl-2-bromine-6-naphthylamine and application thereof UNIV SOUTH CHINA TECH 2015-11-11 CN claimed
CN-101634725-B Blue coloring composition for color filter, color filter and colour display device 东洋油墨制造株式会社 2016-10-05 CN disclosed
CN-105037167-A Synthetic method of N, N-diaryl-2-bromine-6-naphthylamine and application thereof UNIV SOUTH CHINA TECH 2015-11-11 CN disclosed