Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 9/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 4/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.34 |
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675860 | 0.96 | ADRA1A (0.40) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7681624 | 0.93 | ADRA1A (0.38) | ADRA1AMCHR1ADRA1DADRA1BNAAA | |
| SCHEMBL7675275 | 0.90 | ADRA1A (0.43) | ADRA1AMCHR1ADRA1DADRA1BNAAA | |
| SCHEMBL7675324 | 0.85 | ADRA1A (0.44) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7676403 | 0.83 | ADRA1A (0.42) | ADRA1AMCHR1ADRA1DADRA1BNAAA | |
| SCHEMBL7675243 | 0.82 | ADRA1A (0.42) | ADRA1AMCHR1ADRA1DADRA1BNAAA | |
| SCHEMBL7674551 | 0.82 | ADRA1A (0.41) | ADRA1AMCHR1ADRA1DADRA1BNAAA | |
| SCHEMBL7675363 | 0.81 | MCHR1 (0.41) | ADRA1AMCHR1DRD2ADRA1DADRA1B | |
| SCHEMBL7675282 | 0.80 | ADRA1A (0.40) | ADRA1AMCHR1ADRA1DADRA1B | |
| SCHEMBL7672602 | 0.80 | MCHR1 (0.40) | ADRA1AMCHR1ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |