SCHEMBL7678342

SCHEMBL7678342

CC1(C)O[C@@H]2[C@H](O1)[C@@H](CO)O[C@H]2n1cnc2c(S)ncnc21

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PI4KA P42356 2/20 0.77
▸ PI4K2B Q8TCG2 2/20 0.77
▸ PI4K2A Q9BTU6 2/20 0.77
▸ PI4KB Q9UBF8 2/20 0.77
▸ ALDH1A1 P00352 1/20 0.56
▸ LMNA P02545 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56
▸ RXFP1 Q9HBX9 1/20 0.53
▸ P2RX1 P51575 1/20 0.51
▸ P2RX3 P56373 1/20 0.51
▸ P2RX4 Q99571 1/20 0.51
▸ GAA P10253 1/20 0.50
▸ OR51E2 Q9H255 1/20 0.49
▸ AMD1 P17707 2/20 0.48
▸ EGFR P00533 1/20 0.47
▸ ERBB2 P04626 1/20 0.47
▸ ADORA2A P29274 2/20 0.47
▸ SMN1; SMN2 Q16637 2/20 0.47
▸ DPP4 P27487 1/20 0.47
▸ MEN1 O00255 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2291671 0.89 PI4KA (0.80) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL16256552 0.88 PI4KA (0.78) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL30586379 0.88 PI4KA (0.78) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL1795588 0.87 PI4KA (0.77) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL20483753 0.87 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL24146588 0.87 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL21882960 0.87 PI4KA (0.77) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL22393059 0.87 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL17568785 0.87 PI4KA (0.77) PI4KAPI4K2BPI4K2API4KBALDH1A1
SCHEMBL17568786 0.87 PI4KA (1.00) PI4KAPI4K2BPI4K2API4KBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12054768-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-08-06 — — US disclosed
EP-4123031-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME The Regents of The University of California (US) 2023-01-25 — — EP disclosed
EP-3283638-B1 METHODS FOR DETECTING AGGLUTINATION AND USE OF KITS IN PRACTICING THE SAME UNIV CALIFORNIA (US) 2022-06-08 — — EP disclosed
US-20210403978-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2021-12-30 — — US disclosed
US-11149296-B2 Methods for detecting agglutination and compositions for use in practicing the same THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2021-10-19 — — US disclosed
US-10584363-B2 Methods of producing and using single-stranded deoxyribonucleic acids and compositions for use in practicing the same TAKARA BIO USA, INC. (US) 2020-03-10 — — US disclosed
US-20180100181-A1 METHODS FOR DETECTING AGGLUTINATION AND COMPOSITIONS FOR USE IN PRACTICING THE SAME THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2018-04-12 — — US disclosed
US-20170349927-A1 METHODS OF PRODUCING AND USING SINGLE-STRANDED DEOXYRIBONUCLEIC ACIDS AND COMPOSITIONS FOR USE IN PRACTICING THE SAME TAKARA BIO USA, INC. 2017-12-07 — — US disclosed
US-20020061509-A1 Screening assay for the identification of agents which alter expression of PTH-rP OSTEO SCREEN 2002-05-23 — — US disclosed
US-5773424-A PARASITICIDE RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1998-06-30 — — US disclosed
WO-1998007844-A2 SCREENING ASSAY FOR THE IDENTIFICATION OF AGENTS WHICH ALTER EXPRESSION OF PTH-rP OSTEOSCREEN (US) 1998-02-26 — — WO disclosed
US-5213972-A Production of thymidine and deoxyuridine, intermediates for AZT CHEMGEN CORPORATION (US) 1993-05-25 — — US disclosed
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