Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7671177 | 0.90 | MAPT (0.59) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL7849859 | 0.82 | MAPT (0.67) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL7674977 | 0.81 | MAPT (0.64) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL7563359 | 0.80 | MAPT (0.70) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL8241650 | 0.79 | ALDH1A1 (0.85) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL7848449 | 0.79 | MAPT (0.65) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL25609773 | 0.78 | MAPT (0.66) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL7677155 | 0.77 | ALDH1A1 (0.61) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL7849756 | 0.76 | ALDH1A1 (0.67) | MAPTALDH1A1KDM4EL3MBTL1GAA | |
| SCHEMBL26616376 | 0.76 | MAPT (0.67) | MAPTALDH1A1KDM4EL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472418-B1 | Non-peptide NK1 receptors antagonists | WARNER-LAMBERT COMPANY | 2002-10-29 | — | — | US | disclosed |