Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.56 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | GALR2 | O43603 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7159181 | 0.80 | RAB9A (0.58) | RAB9ANPC1PTPN2PTPN1PTPN6 | |
| SCHEMBL7662848 | 0.78 | RAB9A (0.81) | RAB9ANPC1PTPN2PTPN1PTPN6 | |
| SCHEMBL7848327 | 0.78 | RAB9A (0.69) | RAB9ANPC1PTPN2PTPN1PTPN6 | |
| SCHEMBL7778713 | 0.77 | RAB9A (0.67) | RAB9ANPC1PTPN2PTPN1PTPN6 | |
| SCHEMBL7160214 | 0.75 | RAB9A (0.71) | RAB9ANPC1PTPN2PTPN1PTPN6 | |
| SCHEMBL7848400 | 0.74 | RAB9A (0.66) | RAB9ANPC1PTPN2PTPN1PTPN6 | |
| SCHEMBL6632968 | 0.74 | RAB9A (1.00) | RAB9ANPC1PTPN2PTPN1PTPN6 | |
| SCHEMBL7743467 | 0.72 | RAB9A (0.75) | RAB9ANPC1PTPN2PTPN1PTPN6 | |
| SCHEMBL5448328 | 0.72 | RAB9A (0.73) | RAB9ANPC1ALDH1A1KDM4EMAPT | |
| SCHEMBL7159313 | 0.72 | KDM4E (0.64) | RAB9ANPC1ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407123-B1 | VIRICIDES FOR TREATMENT OF HUMAN CYTOMEGALO, EPSTEIN-BARR, VARICELLA-ZOSTER AND KAPOSI*S HERPES VIRAL INFECTIONS | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-18 | — | — | US | disclosed |