Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL188211 | 0.83 | GFER (0.64) | ALDH1A1KMT2AUSP2TSHRMEN1 | |
| SCHEMBL631962 | 0.82 | ALDH1A1 (0.69) | ALDH1A1KMT2AUSP2TSHRMEN1 | |
| SCHEMBL17838736 | 0.81 | AKR1C3 (0.63) | ALDH1A1KMT2AUSP2MEN1MAPT | |
| SCHEMBL5546278 | 0.81 | POLB (0.69) | ALDH1A1KMT2AUSP2TSHRMEN1 | |
| SCHEMBL5795262 | 0.81 | — | — | |
| SCHEMBL17838641 | 0.80 | AKR1C3 (0.66) | ALDH1A1KMT2AUSP2MEN1MAPT | |
| SCHEMBL188791 | 0.80 | AKR1C3 (0.60) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| Hydrochloric Acid SCHEMBL5492248 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KMT2AUSP2TSHRMEN1 | |
| SCHEMBL188410 | 0.79 | MAPK1 (0.46) | ALDH1A1KMT2AMEN1MAPTLMNA | |
| SCHEMBL188783 | 0.79 | NAMPT (0.51) | ALDH1A1KMT2ATSHRMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410533-B1 | THERAPY FOR BACTERIA INFECTIONS | GENZYME CORPORATION | 2002-06-25 | — | — | US | claimed |
| US-6410533-B1 | THERAPY FOR BACTERIA INFECTIONS | GENZYME CORPORATION | 2002-06-25 | — | — | US | disclosed |