Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 18/20 | 0.66 |
| ▸ | ITGAV | P06756 | 18/20 | 0.66 |
| ▸ | NAMPT | P43490 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5878631 | 1.00 | ITGB3 (0.66) | ITGB3ITGAVNAMPT | |
| SCHEMBL5878634 | 1.00 | ITGB3 (0.66) | ITGB3ITGAVNAMPT | |
| SCHEMBL5878092 | 0.91 | ITGB3 (0.65) | ITGB3ITGAV | |
| SCHEMBL5878086 | 0.91 | ITGB3 (0.65) | ITGB3ITGAV | |
| SCHEMBL5878276 | 0.91 | ITGB3 (0.64) | ITGB3ITGAVNAMPT | |
| SCHEMBL5878133 | 0.89 | ITGB3 (0.64) | ITGB3ITGAV | |
| SCHEMBL5878434 | 0.89 | ITGB3 (0.64) | ITGB3ITGAV | |
| SCHEMBL5878482 | 0.87 | ITGB3 (0.62) | ITGB3ITGAVNAMPT | |
| SCHEMBL5878489 | 0.87 | ITGB3 (0.62) | ITGB3ITGAVNAMPT | |
| SCHEMBL5878731 | 0.85 | ITGB3 (0.89) | ITGB3ITGAV |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420396-B1 | TREATMENT OF CANCER, ARTERIOSCLEROSIS, RESTENOSIS, OSTEOLYTIC DISORDERS, OPHTHALMIC DISORDERS, AND THEIR USE AS INTEGRIN ANTAGONISTS. INHIBITING ANGIOGENESIS | BEIERSDORF AG (DE) | 2002-07-16 | — | — | US | disclosed |