Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 7/20 | 0.41 |
| ▸ | CDK4 | P11802 | 4/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 3/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 3/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 3/20 | 0.36 |
| ▸ | KCNJ8 | Q15842 | 3/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | F12 | P00748 | 1/20 | 0.34 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681461 | 0.85 | CDK2 (0.40) | CDK2CDK4CYP2C9TRPM8ABCC9 | |
| SCHEMBL7677622 | 0.83 | CDK2 (0.45) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL20798250 | 0.82 | CDK4 (0.45) | CDK2CDK4CYP2C9TRPM8ALDH1A1 | |
| SCHEMBL7679500 | 0.81 | CDK2 (0.43) | CDK2CDK4TRPM8ABCC9ABCC8 | |
| SCHEMBL7673485 | 0.80 | CDK2 (0.42) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7680787 | 0.79 | CDK2 (0.41) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7682123 | 0.79 | CDK2 (0.43) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7676916 | 0.78 | CDK2 (0.44) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7676510 | 0.78 | CDK2 (0.47) | CDK2CDK4ABCC9ABCC8KCNJ11 | |
| SCHEMBL7676574 | 0.78 | CDK2 (0.50) | CDK2CDK4ABCC9ABCC8KCNJ11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |