Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 6/20 | 0.68 |
| ▸ | F12 | P00748 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18752273 | 0.91 | MEN1 (0.56) | F2F12MEN1KMT2APOLB | |
| SCHEMBL7675773 | 0.89 | F2 (0.59) | F2F12POLBCA12CA2 | |
| SCHEMBL7675741 | 0.88 | F2 (0.60) | F2F12POLBCA12CA9 | |
| SCHEMBL7679435 | 0.84 | F2 (0.60) | F2F12MEN1KMT2APOLB | |
| SCHEMBL14642288 | 0.84 | F2 (0.72) | F2F12MEN1KMT2APOLB | |
| SCHEMBL14642319 | 0.84 | F2 (0.78) | F2F12MEN1KMT2APOLB | |
| SCHEMBL14642287 | 0.83 | F2 (0.77) | F2F12MEN1KMT2APOLB | |
| SCHEMBL18752290 | 0.83 | F2 (0.73) | F2F12MEN1KMT2APOLB | |
| SCHEMBL14642283 | 0.83 | F2 (0.73) | F2F12MEN1KMT2APOLB | |
| SCHEMBL14642286 | 0.81 | F2 (1.00) | F2F12MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9814696-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-11-14 | — | — | US | disclosed |
| US-9814696-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-11-14 | — | — | US | disclosed |
| EP-2731604-B1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIV PIERRE ET MARIE CURIE PARIS 6 (FR) | 2017-04-19 | — | — | EP | disclosed |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2017-03-09 | — | — | US | disclosed |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2017-03-09 | — | — | US | disclosed |
| US-9532973-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2017-01-03 | — | — | US | disclosed |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2015-07-02 | — | — | US | disclosed |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE DE LIEGE (BE) | 2015-07-02 | — | — | US | disclosed |
| US-9006466-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2015-04-14 | — | — | US | disclosed |
| US-9006466-B2 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2015-04-14 | — | — | US | disclosed |
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-05-29 | — | — | US | disclosed |
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2014-05-29 | — | — | US | disclosed |
| WO-2013010963-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) | 2013-01-24 | — | — | WO | disclosed |
| EP-2545916-A1 | Use of coumarin derivatives for the preparation of drugs for treating skin diseases | Universite Pierre Et Marie Curie - Paris 6 (FR) | 2013-01-16 | — | — | EP | disclosed |
| US-6355658-B1 | COUMARIN ESTERS WITH ETHER GROUPS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2002-03-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148480-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, KLK1, SERPINC1 | F2 77/4885F12 15/4885MEN1 913/4885 |
| US-20150182499-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, SERPINC1, KLK1 | F2 76/4885F12 14/4885MEN1 904/4885 |
| US-20170065555-A1 | USE OF COUMARIN DERIVATIVES FOR THE PREPARATION OF DRUGS FOR TREATING SKIN DISEASES | BDKRB1, SERPINC1, KLK1 | F2 76/4885F12 14/4885MEN1 904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.