Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.47 |
| ▸ | FNTB | P49356 | 7/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 2/20 | 0.39 |
| ▸ | MC3R | P41968 | 2/20 | 0.39 |
| ▸ | MC1R | Q01726 | 2/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6617793 | 1.00 | FNTA (0.47) | FNTAFNTBPARP1MC4RMC3R | |
| SCHEMBL5788247 | 0.89 | FNTA (0.47) | FNTAFNTBMGLLNAMPTNR3C2 | |
| SCHEMBL5788241 | 0.89 | FNTA (0.47) | FNTAFNTBMGLLNAMPTNR3C2 | |
| SCHEMBL7688068 | 0.88 | FNTA (0.47) | FNTAFNTBMGLLNAMPTNR3C2 | |
| SCHEMBL6637279 | 0.88 | FNTA (0.47) | FNTAFNTBMGLLNAMPTNR3C2 | |
| SCHEMBL6633950 | 0.84 | FNTA (0.44) | FNTAFNTBMGLLNAMPT | |
| SCHEMBL6633953 | 0.84 | FNTA (0.44) | FNTAFNTBMGLLNAMPT | |
| SCHEMBL6619143 | 0.84 | FNTA (0.49) | FNTAFNTBMGLLDPP4 | |
| Benzoyl Chloride SCHEMBL6627979 | 0.84 | FNTA (0.44) | FNTAFNTBMGLLNAMPTNR3C2 | |
| SCHEMBL6634181 | 0.84 | FNTA (0.49) | FNTAFNTBMGLLDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-6011029-A | BENZODIAZEPINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-01-04 | — | — | US | disclosed |