Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 7/20 | 0.47 |
| ▸ | FNTB | P49356 | 7/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | GLP1R | P43220 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6637279 | 1.00 | FNTA (0.47) | FNTAFNTBABCB1CA1CA2 | |
| Benzoyl Chloride SCHEMBL6627979 | 0.95 | FNTA (0.44) | FNTAFNTBABCB1CA1CA2 | |
| SCHEMBL6633950 | 0.88 | FNTA (0.44) | FNTAFNTBALDH1A1NAMPTMGLL | |
| SCHEMBL6633953 | 0.88 | FNTA (0.44) | FNTAFNTBALDH1A1NAMPTMGLL | |
| SCHEMBL7679452 | 0.88 | FNTA (0.47) | FNTAFNTBCA1CA2CA4 | |
| SCHEMBL6617793 | 0.88 | FNTA (0.47) | FNTAFNTBCA1CA2CA4 | |
| SCHEMBL5788247 | 0.85 | FNTA (0.47) | FNTAFNTBNAMPTNR3C2MGLL | |
| SCHEMBL5788241 | 0.85 | FNTA (0.47) | FNTAFNTBNAMPTNR3C2MGLL | |
| SCHEMBL6619143 | 0.84 | FNTA (0.49) | FNTAFNTBABCB1MGLL | |
| SCHEMBL6634181 | 0.84 | FNTA (0.49) | FNTAFNTBABCB1MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6455523-B1 | ADMINISTERING 1,4-BENZODIAZEPINE DERIVATIVE AS ANTITUMOR OR ANTICARCINOGENIC AGENT | BRISTOL-MYERS SQUIBB COMPANY | 2002-09-24 | — | — | US | disclosed |
| US-6011029-A | BENZODIAZEPINE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-01-04 | — | — | US | disclosed |