⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411308 | 0.89 | CA1 (0.32) | — | |
| SCHEMBL6931736 | 0.85 | — | — | |
| SCHEMBL14820781 | 0.85 | — | — | |
| SCHEMBL27946743 | 0.84 | TDP1 (0.38) | — | |
| SCHEMBL9323325 | 0.83 | DNM1 (0.42) | — | |
| SCHEMBL15392539 | 0.82 | — | — | |
| SCHEMBL24830110 | 0.81 | DNM1 (0.45) | — | |
| SCHEMBL9322467 | 0.81 | DNM1 (0.45) | — | |
| SCHEMBL23890643 | 0.80 | — | — | |
| SCHEMBL1562985 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | claimed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | claimed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | claimed |
| CN-103965023-A | Fluoroalkylvinyl ether preparation method | SINOCHEM LANTIAN CO LTD | 2014-08-06 | — | — | CN | disclosed |
| CN-103864583-A | Heptafluoropropyl-1,2,2,2-tetrafluoroethyl ether preparation method | SINOCHEM LANTIAN CO LTD | 2014-06-18 | — | — | CN | disclosed |
| US-6380197-B1 | FOR TREATING AND PREVENTING A PLETHORA OF DISEASES INCLUDING DIABETES | AVENTIS PHARMA S. A. (FR) | 2002-04-30 | — | — | US | disclosed |
| EP-1001943-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | Aventis Pharma S.A. (FR) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999003843-A1 | POLYHYDROXYALKYLPYRAZINE DERIVATIVES, PREPARATION AND MEDICINES CONTAINING THEM | RHONE-POULENC RORER S.A. (FR) | 1999-01-28 | — | — | WO | disclosed |
| US-4639436-A | Antidiabetic 3,4,5-trihydroxypiperidines | BAYER AKTIENGESELLSCHAFT (DE) | 1987-01-27 | — | — | US | disclosed |
| EP-0193770-A2 | 3,4,5-Trihydroxypiperidine, process for their preparation and their use | BAYER AG (DE) | 1986-09-10 | — | — | EP | disclosed |
| EP-0000947-B2 | 3,4,5-TRIHYDROXYPIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS AND FODDER CONTAINING THEM | BAYER AG (DE) | 1984-10-10 | — | — | EP | disclosed |
| EP-0008058-B1 | N-AMINO-3,4,5-TRIHYDROXYPIPERIDINES, METHODS FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM, METHOD FOR THE PRODUCTION OF THE MEDICAMENTS AND ANIMAL FEEDSTUFF CONTAINING SAID COMPOUNDS | BAYER AG (DE) | 1982-08-18 | — | — | EP | disclosed |
| US-4293551-A | N-Amino-3,4,5-trihydroxypiperidines, their production and their medicinal use | BAYER AKTIENGESELLSCHAFT (DE) | 1981-10-06 | — | — | US | disclosed |
| US-4260622-A | Animal feedstuffs employing 3,4,5-trihydroxypiperidines | BAYER AKTIENGESELLSCHAFT (DE) | 1981-04-07 | — | — | US | disclosed |
| EP-0000947-B1 | 3,4,5-TRIHYDROXYPIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND MEDICAMENTS AND FODDER CONTAINING THEM | BAYER AG (DE) | 1981-01-14 | — | — | EP | disclosed |
| US-4199572-A | DERIVATIVES OF SISOMICINS | BAYER AKTIENGESELLSCHAFT (DE) | 1980-04-22 | — | — | US | disclosed |
| EP-0008058-A1 | N-Amino-3,4,5-trihydroxypiperidines, methods for their preparation, medicaments containing them, method for the production of the medicaments and animal feedstuff containing said compounds | BAYER AG (DE) | 1980-02-20 | — | — | EP | disclosed |