Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 14/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 13/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 13/20 | 0.56 |
| ▸ | PTGIR | P43119 | 3/20 | 0.51 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.48 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4689875 | 0.99 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL7684044 | 0.89 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| Hydrochloric Acid SCHEMBL4690857 | 0.88 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL7682578 | 0.87 | ADRA2A (0.55) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL4689990 | 0.85 | ADRA2A (0.64) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| Hydrochloric Acid SCHEMBL4687587 | 0.81 | PTGIR (0.67) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL4689983 | 0.79 | ADRA2A (0.61) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL4690853 | 0.78 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| Hydrochloric Acid SCHEMBL4690851 | 0.78 | ADRA2A (0.69) | ADRA2AADRA2BADRA2CPTGIRGPR65 | |
| SCHEMBL4687665 | 0.78 | PTGIR (0.51) | ADRA2AADRA2BADRA2CPTGIRGPR65 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6472536-B1 | SUCH AS 2-(4-(4-CYCLOPENTYLOXYBENZYL)PHENYL)AMINO-IMIDAZOLINE; ANTINOCICEPTIVE AGENTS; IP RECEPTOR ANTAGONISTS; TREATING INFLAMMATORY PAIN | SYNTEX (U.S.A.) LLC | 2002-10-29 | — | — | US | claimed |