Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.51 |
| ▸ | PDE4A | P27815 | 4/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680045 | 1.00 | ALDH1A1 (0.59) | ALDH1A1MAPTSMN1; SMN2HPGDCNR2 | |
| SCHEMBL6228384 | 0.82 | MAPT (0.59) | ALDH1A1MAPTSMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL6942920 | 0.82 | MAPT (0.59) | ALDH1A1MAPTSMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL7545268 | 0.80 | MAPT (0.60) | ALDH1A1MAPTSMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL19649051 | 0.79 | HPGD (0.67) | ALDH1A1MAPTSMN1; SMN2HPGDCYP1A1 | |
| SCHEMBL7359690 | 0.79 | PDE4A (0.55) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL6949716 | 0.79 | MAPT (0.55) | ALDH1A1MAPTSMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL6950497 | 0.79 | MAPT (0.55) | ALDH1A1MAPTSMN1; SMN2HPGDCYP1A2 | |
| SCHEMBL7359689 | 0.79 | PDE4A (0.55) | ALDH1A1SMN1; SMN2PDE4APDE4BPDE4C | |
| SCHEMBL7680043 | 0.78 | PDE4B (0.57) | ALDH1A1CNR2PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020143011-A1 | Tri-substituted phenyl derivatives and processes for their preparation | CELLTECH THERAPEUTICS, LIMITED | 2002-10-03 | — | — | US | disclosed |
| US-6245774-B1 | ANTIINFLAMMATORY AGENTS; BRONCHODILATOR AGENTS | CELLTECH THERAPEUTICS LIMITED (GB) | 2001-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143011-A1 | Tri-substituted phenyl derivatives and processes for their preparation | CBR1, NCOR1, CNR1 | ALDH1A1 2785/4885MAPT 3885/4885SMN1; SMN2 1142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.