Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 2/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 4/20 | 0.39 |
| ▸ | CDK4 | P11802 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | AKT2 | P31751 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7676921 | 0.88 | AKT1 (0.45) | USP7CDK2CDK4AKT1AKT2 | |
| SCHEMBL7673714 | 0.86 | LRRK2 (0.37) | PIK3CDPIK3CAPIK3CGMEN1NPC1 | |
| SCHEMBL7683036 | 0.84 | CDK2 (0.41) | USP7PIK3CDPIK3CGCDK2CDK4 | |
| SCHEMBL7675252 | 0.84 | CDK2 (0.53) | USP7CDK2CDK4MEN1NPC1 | |
| SCHEMBL7676881 | 0.81 | CDK2 (0.41) | USP7CDK2CDK4AKT1AKT2 | |
| SCHEMBL7681426 | 0.78 | CDK2 (0.46) | CDK2CDK4AKT1AKT2 | |
| SCHEMBL7683354 | 0.78 | CDK2 (0.42) | CDK2CDK4 | |
| SCHEMBL7680593 | 0.77 | CDK2 (0.42) | CDK2CDK4 | |
| SCHEMBL7674268 | 0.76 | AKT1 (0.39) | USP7CDK2CDK4MEN1RAB9A | |
| SCHEMBL7676656 | 0.76 | CDK2 (0.48) | CDK2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |