Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 18/20 | 0.42 |
| ▸ | CDK4 | P11802 | 9/20 | 0.42 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680593 | 0.88 | CDK2 (0.42) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676881 | 0.88 | CDK2 (0.41) | CDK2CDK4 | |
| SCHEMBL7683036 | 0.86 | CDK2 (0.41) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7681340 | 0.84 | KIF11 (0.33) | CDK2CDK4CCNE1KIF11MAPK14 | |
| SCHEMBL7676327 | 0.83 | CDK2 (0.58) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676921 | 0.83 | AKT1 (0.45) | CDK2CDK4 | |
| SCHEMBL7673974 | 0.81 | CDK2 (0.60) | CDK2CDK4 | |
| SCHEMBL7680064 | 0.78 | USP7 (0.41) | CDK2CDK4 | |
| SCHEMBL7676656 | 0.77 | CDK2 (0.48) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676802 | 0.77 | CDK2 (0.59) | CDK2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |