Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.44 |
| ▸ | RAB7A | P51149 | 3/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 7/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.40 |
| ▸ | PTPRB | P23467 | 2/20 | 0.40 |
| ▸ | PTPRE | P23469 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5837862 | 0.92 | PTPN1 (0.45) | PTPN1RAB7APTPN2PTPRCPTPRB | |
| SCHEMBL6317112 | 0.85 | PTPN1 (0.44) | PTPN1RAB7APTPN2PTPRCPTPRB | |
| SCHEMBL6317331 | 0.80 | SMN1; SMN2 (0.45) | PTPN1RAB7APTPN2PTPRCPTPRB | |
| SCHEMBL7676326 | 0.78 | PTPN1 (0.49) | PTPN1RAB7APTPN2PTPRCPTPRB | |
| SCHEMBL6206528 | 0.77 | RAB7A (0.55) | PTPN1RAB7APTPN2PTPRCPTPRB | |
| SCHEMBL6322930 | 0.75 | PTPN1 (0.47) | PTPN1RAB7APTPN2PTPRCPTPRB | |
| SCHEMBL6316036 | 0.75 | PTPN1 (0.47) | PTPN1RAB7APTPN2PTPRCPTPRB | |
| SCHEMBL6323697 | 0.75 | PTPN1 (0.45) | PTPN1RAB7APTPN2PTPRCPTPRB | |
| SCHEMBL6395534 | 0.75 | SMN1; SMN2 (0.50) | PTPN1RAB7APTPN2PTPRCPTPRB | |
| SCHEMBL6316713 | 0.75 | RAB7A (0.45) | PTPN1RAB7APTPN2PTPRCPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410586-B1 | ANTICOAGULANTS; INSULIN RESISTANCE; ANTIALLERGENS | NOVO NORDISK A/S (DK) | 2002-06-25 | — | — | US | claimed |