Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 2/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7680113 | 1.00 | EPHX2 (0.36) | EPHX2ALDH1A1MAPTHPGDNPSR1 | |
| SCHEMBL6158523 | 0.91 | — | — | |
| SCHEMBL6158526 | 0.91 | — | — | |
| SCHEMBL6159867 | 0.88 | POLB (0.35) | ALDH1A1MAPTHPGD | |
| SCHEMBL6159862 | 0.88 | POLB (0.35) | ALDH1A1MAPTHPGD | |
| SCHEMBL6163948 | 0.79 | — | — | |
| SCHEMBL6163944 | 0.79 | — | — | |
| SCHEMBL6162431 | 0.79 | P2RX7 (0.35) | — | |
| SCHEMBL6159838 | 0.75 | PPARG (0.39) | — | |
| SCHEMBL7085195 | 0.74 | P2RX7 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479531-B1 | Gastrin and cholecystokinin receptor ligands | JAMES BLACK FOUNDATION LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |