Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6177056 | 0.91 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2KDM4EPLAUPOLB | |
| SCHEMBL7672722 | 0.79 | KDM4E (0.40) | ALDH1A1SMN1; SMN2KDM4EPLAUPOLB | |
| SCHEMBL6742514 | 0.78 | COMT (0.34) | HSD11B1 | |
| SCHEMBL24485245 | 0.77 | ALDH1A1 (0.42) | ALDH1A1SMN1; SMN2KDM4EPLAUPOLB | |
| SCHEMBL7674890 | 0.74 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2KDM4EPLAUPOLB | |
| SCHEMBL7713824 | 0.73 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2KDM4EPLAUPOLB | |
| SCHEMBL8030828 | 0.73 | ALDH1A1 (0.39) | ALDH1A1SMN1; SMN2KDM4EPLAUPOLB | |
| SCHEMBL7676064 | 0.73 | PTGDR2 (0.42) | ALDH1A1SMN1; SMN2KDM4EPKMHPGD | |
| SCHEMBL7676069 | 0.73 | PTGDR2 (0.42) | ALDH1A1SMN1; SMN2KDM4EPKMHPGD | |
| SCHEMBL24485243 | 0.73 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EPLAUPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420314-B1 | GRIGNARD ARYLATION OF A 3-FLUOROPYRIDINE; DESICCANTS, DEFOLIANTS; SELECTIVITY; ACTING AGAINST BROAD-LEAF AND GRASS WEEDS IN CROPS SUCH AS WHEAT, RICE, MAIZE, SOYA AND COTTON | BASF AKTIENGESELLSCHAFT (DE) | 2002-07-16 | — | — | US | disclosed |
| EP-0984933-A1 | SUBSTITUTED 2-PHENYL PYRIDINES, THEIR MANUFACTURE AND USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998054137-A1 | SUBSTITUTED 2-PHENYL PYRIDINES, THEIR MANUFACTURE AND USE AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1998-12-03 | — | — | WO | disclosed |