Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.67 |
| ▸ | FAAH | O00519 | 2/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.57 |
| ▸ | RAD52 | P43351 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3713011 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 | |
| SCHEMBL2976989 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 | |
| SCHEMBL1982370 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 | |
| SCHEMBL3711322 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 | |
| SCHEMBL3209842 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 | |
| SCHEMBL207689 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 | |
| SCHEMBL17812546 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 | |
| SCHEMBL3209973 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 | |
| SCHEMBL240374 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 | |
| SCHEMBL235596 | 0.94 | NAAA (0.75) | NAAAFAAHEPHX1RAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6494950-B1 | FOUR ESSENTIAL COMPONENTS (A) AN ELECTRON-DONATING CHROMATIC ORGANIC COMPOUND, (B) AN ELECTRON-ACCEPTING COMPOUND, (C) A REACTION MEDIUM DETERMINING THE TEMPERATURES AT WHICH THE COLOR REACTIONS OF COMPONENT (A) WITH COMPONENT (B) TAKE | THE PILOT INK CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |