Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 8/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CTSA | P10619 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675912 | 0.88 | MAPK1 (0.34) | KMT2AALDH1A1MAPTCTSAMEN1 | |
| SCHEMBL7681919 | 0.86 | CASP1 (0.38) | CASP1KMT2ACASP3ALDH1A1NPC1 | |
| SCHEMBL7677980 | 0.86 | CASP1 (0.34) | CASP1KMT2ACASP3ALDH1A1MAPT | |
| SCHEMBL7679421 | 0.85 | CASP1 (0.43) | CASP1KMT2ACASP3ALDH1A1MEN1 | |
| SCHEMBL7686197 | 0.84 | CASP1 (0.37) | CASP1KMT2ACASP3ALDH1A1NPC1 | |
| SCHEMBL7676849 | 0.84 | CASP1 (0.38) | CASP1KMT2ACASP3ALDH1A1MAPT | |
| SCHEMBL8165543 | 0.83 | CASP1 (0.35) | CASP1KMT2ACASP3ALDH1A1NPC1 | |
| SCHEMBL7683990 | 0.83 | CASP1 (0.40) | CASP1CASP3 | |
| SCHEMBL7677095 | 0.82 | CASP1 (0.36) | CASP1CASP3CTSA | |
| SCHEMBL7675762 | 0.82 | CASP1 (0.37) | CASP1KMT2ACASP3ALDH1A1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |