Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PI4KA | P42356 | 1/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.47 |
| ▸ | AHCY | P23526 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.44 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6572781 | 1.00 | PI4KA (0.47) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL6574541 | 0.88 | PI4KA (0.48) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL7662387 | 0.86 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL6914454 | 0.86 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL6574588 | 0.86 | PI4KA (0.46) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL23080211 | 0.83 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL6573811 | 0.83 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL13975991 | 0.83 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL21139456 | 0.83 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBAHCY | |
| SCHEMBL14075793 | 0.83 | PI4KA (0.52) | PI4KAPI4K2BPI4K2API4KBAHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492348-B1 | Adenosine derivatives | SMITHKLINE BEECHAM CORPORATION | 2002-12-10 | — | — | US | disclosed |