Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 19/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687264 | 0.88 | CRHR1 (0.79) | CRHR1 | |
| SCHEMBL7678011 | 0.84 | CRHR1 (0.81) | CRHR1 | |
| SCHEMBL7676550 | 0.84 | CRHR1 (0.79) | CRHR1 | |
| SCHEMBL7680501 | 0.81 | CRHR1 (0.64) | CRHR1 | |
| SCHEMBL7678298 | 0.81 | CRHR1 (0.74) | CRHR1 | |
| SCHEMBL7681078 | 0.80 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL7676328 | 0.79 | CRHR1 (0.66) | CRHR1 | |
| SCHEMBL7680481 | 0.79 | CRHR1 (0.70) | CRHR1 | |
| SCHEMBL7684872 | 0.78 | CRHR1 (0.68) | CRHR1 | |
| SCHEMBL7680317 | 0.78 | CRHR1 (0.69) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | claimed |
| WO-1995010506-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-20 | — | — | WO | claimed |
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-6107301-A | PSYCHOLOGICAL DISORDERS | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| WO-1995010506-A1 | 1N-ALKYL-N-ARYLPYRIMIDINAMINES AND DERIVATIVES THEREOF | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1995-04-20 | — | — | WO | disclosed |