Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857482 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL4982453 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL8857143 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL9213355 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL1926091 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL9208656 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL95733 | 0.96 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL277225 | 0.96 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL7697182 | 0.96 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL4399689 | 0.96 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359122-B1 | Pyrocarbonic acid diesters and the preparation and use thereof | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-03-19 | — | — | US | disclosed |
| US-6222047-B1 | PIGMENT PRECURSORS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-04-24 | — | — | US | disclosed |
| EP-0764628-B1 | Diesters of pyrocarbonic acid, their preparation and their use | CIBA SC HOLDING AG (CH) | 2001-03-14 | — | — | EP | disclosed |
| US-5750758-A | DEHYDRATION OF CARBONIC ACID | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1998-05-12 | — | — | US | disclosed |
| EP-0764628-A1 | Diesters of pyrocarbonic acid, their preparation and their use | Ciba SC Holding AG (CH) | 1997-03-26 | — | — | EP | disclosed |
| EP-0421441-B1 | Pantothenic acid derivatives | FUJIREBIO KK (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |