Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857482 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL4982453 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL7680901 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL8857143 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL9213355 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL9208656 | 1.00 | TSHR (0.57) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL95733 | 0.96 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL277225 | 0.96 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL7697182 | 0.96 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA | |
| SCHEMBL4399689 | 0.96 | TSHR (0.61) | TSHRTHRBMEN1KMT2ANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233786-B | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2021-11-26 | — | — | CN | claimed |
| CN-111233786-A | Benzene sulfonamide compound containing five-membered heterocycle and preparation method and application thereof | 中国人民解放军军事科学院军事医学研究院 | 2020-06-05 | — | — | CN | claimed |
| WO-2024137742-A1 | COMPOUNDS AND COMPOSITIONS AS FGFR3 DEGRADERS AND USES THEREOF | BLUEPRINT MEDICINES CORPORATION (US) | 2024-06-27 | — | — | WO | disclosed |
| US-12018267-B2 | Plants having increased tolerance to herbicides | BASF SE (DE) | 2024-06-25 | — | — | US | disclosed |
| WO-2024130095-A1 | COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-06-20 | — | — | WO | disclosed |
| US-11992012-B2 | Diaminotriazine compounds | BASF SE (DE) | 2024-05-28 | — | — | US | disclosed |
| EP-4370505-A1 | HERBICIDAL PHENYLURACILS | BASF SE (DE) | 2024-05-22 | — | — | EP | disclosed |
| WO-2024103067-A1 | COMPOUNDS AND COMPOSITIONS AS eIF4E INHIBITORS AND USES THEREOF | RIBOMETRIX, INC. (US) | 2024-05-16 | — | — | WO | disclosed |
| WO-2024103069-A1 | COMPOUNDS AND COMPOSITIONS AS eIF4E INHIBITORS AND USES THEREOF | RIBOMETRIX, INC. (US) | 2024-05-16 | — | — | WO | disclosed |
| WO-2024086644-A1 | CEREBLON LIGANDS AND USES THEREOF | ONCOPIA THERAPEUTICS, INC. D/B/A/ SK LIFE SCIENCE LABS (US) | 2024-04-25 | — | — | WO | disclosed |
| US-11965171-B2 | Plants having increased tolerance to herbicides | BASF SE (DE) | 2024-04-23 | — | — | US | disclosed |
| EP-0994108-A1 | PROCESS FOR PRODUCING 2-HYDROXYBENZAMIDE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-19 | — | — | EP | disclosed |
| EP-0945445-A1 | 1,5-BENZODIAZEPINE DERIVATIVES | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |
| US-5688823-A | ANTILIPEMIC AGENTS, ANTIGLYCEMIC AGENTS, OBESITY, GLUCOSE TOLERANCE INSUFFICIENCY, INSULIN RESISTANCE AND DIABETIC COMPLICATIONS | SANKYO COMPANY, LIMITED (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5578620-A | TREATMENT OF DIABETES AND HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1996-11-26 | — | — | US | disclosed |
| EP-0678511-A2 | Thiazolidine and oxazolidine derivatives, their preparation and their medical use | SANKYO COMPANY LIMITED (JP) | 1995-10-25 | — | — | EP | disclosed |
| EP-0148725-B1 | SULFONAMIDO-BENZAMIDE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1987-05-06 | — | — | EP | disclosed |
| US-4595780-A | Sulfonamido-benzamide derivatives | SHIONOGI & CO., LTD. (JP) | 1986-06-17 | — | — | US | disclosed |
| EP-0148725-A1 | Sulfonamido-benzamide derivatives | SHIONOGI & CO., LTD. (JP) | 1985-07-17 | — | — | EP | disclosed |
| US-4182887-A | ANTIPHLOGISTIC, ANTITHROMBOTIC | BOEHRINGER INGELHEIM GMBH (DE) | 1980-01-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11965171-B2 | Plants having increased tolerance to herbicides | CES2, PFAS, RNGTT | TSHR 3097/4885THRB 3976/4885MEN1 4556/4885 |
| US-11992012-B2 | Diaminotriazine compounds | DDT, DAZAP1, DDC | TSHR 3261/4885THRB 3578/4885MEN1 3474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.