Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7683034 | 0.85 | PRKCI (0.46) | KDM4ENPSR1L3MBTL1TLR8HDAC1 | |
| SCHEMBL7687751 | 0.81 | PRKCI (0.45) | KDM4ENPSR1L3MBTL1TLR8HDAC1 | |
| SCHEMBL7685581 | 0.80 | ALDH1A1 (0.42) | KDM4EL3MBTL1KMT2APDE4BPDE7A | |
| SCHEMBL7677206 | 0.80 | PRKCI (0.44) | KDM4ENPSR1L3MBTL1TLR8HDAC1 | |
| SCHEMBL7680936 | 0.80 | PRKCI (0.44) | KDM4ENPSR1L3MBTL1TLR8HDAC1 | |
| SCHEMBL7677137 | 0.80 | PRKCI (0.44) | KDM4ENPSR1L3MBTL1TLR8HDAC1 | |
| SCHEMBL7686027 | 0.78 | PDE7A (0.35) | KMT2APDE4BPDE7A | |
| SCHEMBL2920664 | 0.76 | PRKCI (0.48) | HDAC1HDAC2HDAC3HDAC4HDAC7 | |
| SCHEMBL7679236 | 0.75 | PDE4B (0.37) | PDE4BPDE7A | |
| SCHEMBL23498347 | 0.74 | SMN1; SMN2 (0.47) | KDM4EHTR6KMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6339089-B2 | ANTIHYPOXIC AGENTS; CHRONIC OBSTRUCTIVE PULMONARY DISEASE; VASOCONSTRICTION; REDUCES BLOOD PARTIAL PRESSURE OF CARBON DIOXIDE; RESPIRATORY DISORDERS; UNDER OXYGEN INHALATION TREATMENT | FUJIREBIO INC. (JP) | 2002-01-15 | — | — | US | disclosed |