Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16595708 | 0.76 | PNMT (0.39) | GRM7MTNR1AMTNR1BKEAP1NFE2L2 | |
| SCHEMBL26939697 | 0.75 | ELANE (0.42) | GRM7MTNR1AMTNR1BKEAP1NFE2L2 | |
| SCHEMBL15057650 | 0.75 | PNMT (0.56) | MEN1KMT2A | |
| SCHEMBL11582234 | 0.74 | MEN1 (0.34) | MTNR1AMTNR1BCYP2C19HIF1AMAPT | |
| SCHEMBL11527510 | 0.74 | ANPEP (0.38) | — | |
| SCHEMBL19393174 | 0.73 | IDO1 (0.41) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL12205541 | 0.72 | HDAC4 (0.46) | MTNR1AMTNR1BRIPK1 | |
| SCHEMBL12205621 | 0.72 | ACP3 (0.44) | MTNR1BCYP2C19RIPK1MEN1KMT2A | |
| SCHEMBL26939292 | 0.71 | CYP2C19 (0.39) | GRM7MTNR1AMTNR1BCYP2C19HIF1A | |
| SCHEMBL24974992 | 0.70 | IDO1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362141-B1 | ORGANOLEPTIC; PERFUMES, COSMETICS, CLEANING COMPOUNDS | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-03-26 | — | — | US | disclosed |
| US-6342612-B1 | FRAGRANCES | INTERNATIONAL FLAVORS & FRAGRANCES INC. | 2002-01-29 | — | — | US | disclosed |