Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.67 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.67 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.67 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL477399 | 0.89 | SMN1; SMN2 (0.65) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL257973 | 0.85 | CYP19A1 (0.59) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL11196968 | 0.85 | CYP19A1 (0.59) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL8737044 | 0.85 | CYP19A1 (0.59) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL2907043 | 0.85 | CYP19A1 (0.68) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL23882924 | 0.85 | CYP19A1 (0.59) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL5512809 | 0.85 | CYP19A1 (0.59) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL3543535 | 0.82 | CYP19A1 (0.55) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL18228789 | 0.82 | SMN1; SMN2 (0.81) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 | |
| SCHEMBL1892118 | 0.81 | CYP3A4 (0.48) | CYP3A4CYP19A1CYP11B1CYP11B2CYP17A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104926888-B | A kind of cobalt complex and preparation method and application | 南京信息工程大学 | 2017-09-19 | — | — | CN | claimed |
| US-6342503-B1 | ANTIDEPRESSANTS, EATING DISORDERS | DUPONT PHARMACEUTICALS COMPANY | 2002-01-29 | — | — | US | disclosed |
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0363212-B1 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5204348-A | Quinoline derivatives | MITSUI TOATSU CHEMICALS INC. (JP) | 1993-04-20 | — | — | US | disclosed |
| US-5112817-A | Anticancer Drug Potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1992-05-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |