Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 14/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 3/20 | 0.45 |
| ▸ | DRD3 | P35462 | 3/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677837 | 0.91 | DRD2 (0.59) | DRD2SIGMAR1PDK2ADRA1ACNR2 | |
| SCHEMBL7681348 | 0.89 | DRD2 (0.51) | DRD2SIGMAR1PDK2ADRA1ACNR2 | |
| SCHEMBL7681697 | 0.82 | DRD2 (0.52) | DRD2SIGMAR1ADRA1A | |
| SCHEMBL7234672 | 0.82 | DRD2 (0.59) | DRD2SIGMAR1DRD4DRD3ADRA1A | |
| SCHEMBL7672325 | 0.81 | DRD2 (0.51) | DRD2SIGMAR1PDK2ADRA1A | |
| SCHEMBL7681665 | 0.80 | DRD2 (0.56) | DRD2SIGMAR1ADRA1ACNR2 | |
| SCHEMBL7674334 | 0.80 | DRD2 (0.56) | DRD2SIGMAR1ADRA1ACNR2 | |
| SCHEMBL7675375 | 0.79 | DRD2 (0.55) | DRD2SIGMAR1ADRA1ACNR2 | |
| SCHEMBL7675331 | 0.79 | DRD2 (0.54) | DRD2SIGMAR1ADRA1ACNR2 | |
| SCHEMBL7675117 | 0.77 | DRD2 (0.42) | DRD2SIGMAR1PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6387893-B1 | ADRENERGIC BLOCKING AGENT; BENIGN PROSATATIC HYPERPLASIA | MERCK & CO., INC. | 2002-05-14 | — | — | US | disclosed |