Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14557079 | 0.87 | CXCR4 (0.52) | POLBLMNARECQLMAPTMEN1 | |
| SCHEMBL5199559 | 0.84 | TNF (0.65) | LMNAMAPTMEN1KMT2AKDM4E | |
| SCHEMBL14557060 | 0.82 | CXCR4 (0.61) | POLBLMNAMAPTALDH1A1TP53 | |
| SCHEMBL9671285 | 0.81 | MEN1 (0.69) | LMNARECQLMAPTMEN1KMT2A | |
| SCHEMBL3140332 | 0.81 | POLB (0.65) | POLBLMNARECQLMAPTMEN1 | |
| SCHEMBL8659167 | 0.81 | KDM4E (0.54) | POLBLMNAMEN1KMT2AKDM4E | |
| SCHEMBL540958 | 0.79 | TNF (0.73) | POLBLMNARECQLMAPTMEN1 | |
| SCHEMBL11715808 | 0.79 | CXCR4 (0.72) | POLBLMNARECQLMAPTMEN1 | |
| SCHEMBL31357207 | 0.79 | KDM4E (0.65) | POLBLMNAKMT2AKDM4EL3MBTL1 | |
| SCHEMBL11104091 | 0.79 | KDM4E (0.65) | POLBLMNAKMT2AKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119452041-A | Composition and method for producing the same | 默克专利有限公司 | 2025-02-14 | — | — | CN | disclosed |
| US-6376666-B1 | PSYCHOLOGICAL DISORDERS; CARDIOVASCUALR DISORDERS | NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII ROSSIISKOI AKADEMII MEDITSINSKIKH NAUK (RU) | 2002-04-23 | — | — | US | disclosed |
| EP-0788795-A1 | PHARMACOLOGICALLY ACTIVE 2-MERCAPTOBENZIMIDAZOLE DERIVATIVES | NAUCHNO-ISSLEDOVATELSKY INSTITUT FARMAKOLOGII AKADEMII MEDITSINSKIKH NAUK (RU) | 1997-08-13 | — | — | EP | disclosed |
| EP-0190817-B1 | DOPAMINE-BETA-HYDROXYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4857540-A | 1-SUBSTITUTED-2-MERCAPTO-(OR AMINOMETHYL-)BENZAMIDAZOLE COMPOUNDS | SMITHKLINE BECKMAN CORPORATION (US) | 1989-08-15 | — | — | US | disclosed |
| US-4728741-A | DOPAMINE BETA-HYDROXYLASE INHIBITOR | SMITHKLINE BECKMAN CORPORATION (US) | 1988-03-01 | — | — | US | disclosed |
| EP-0190817-A1 | Dopamine-beta-hydroxylase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 1986-08-13 | — | — | EP | disclosed |