Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 20/20 | 0.48 |
| ▸ | FNTB | P49356 | 20/20 | 0.48 |
| ▸ | PGGT1B | P53609 | 17/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679247 | 0.82 | FNTA (0.50) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL4459587 | 0.80 | FNTA (0.53) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8095394 | 0.80 | FNTA (0.60) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7673415 | 0.79 | FNTA (0.52) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7678087 | 0.79 | FNTA (0.51) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL7682600 | 0.79 | FNTA (0.53) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8441677 | 0.76 | FNTA (0.55) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8103727 | 0.76 | FNTA (0.55) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8088609 | 0.75 | FNTA (0.61) | FNTAFNTBPGGT1BKCNH2 | |
| SCHEMBL8095374 | 0.75 | FNTA (0.61) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432959-B1 | ANTITUMOR AGENTS | SCHERING CORPORATION | 2002-08-13 | — | — | US | disclosed |
| EP-1140909-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039119-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |