Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.51 |
| ▸ | FNTB | P49356 | 18/20 | 0.51 |
| ▸ | PGGT1B | P53609 | 17/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682600 | 0.94 | FNTA (0.53) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7673415 | 0.93 | FNTA (0.52) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL4459587 | 0.91 | FNTA (0.53) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7679247 | 0.85 | FNTA (0.50) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8095394 | 0.81 | FNTA (0.60) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL4409108 | 0.79 | MMP1 (0.49) | FNTAFNTBPGGT1B | |
| SCHEMBL8103587 | 0.79 | ALDH1A1 (0.57) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8104389 | 0.79 | ALDH1A1 (0.57) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL8423622 | 0.79 | ALDH1A1 (0.57) | FNTAFNTBPGGT1BCYP11B1CYP11B2 | |
| SCHEMBL7681229 | 0.79 | FNTA (0.48) | FNTAFNTBPGGT1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6432959-B1 | ANTITUMOR AGENTS | SCHERING CORPORATION | 2002-08-13 | — | — | US | disclosed |
| EP-1140909-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039119-A1 | NOVEL INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | SCHERING CORPORATION (US) | 2000-07-06 | — | — | WO | disclosed |