Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | FABP3 | P05413 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.34 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5898752 | 0.83 | HSD17B10 (0.32) | MAPTALDH1A1KDM4ETSHRSMN1; SMN2 | |
| SCHEMBL13740669 | 0.72 | PTGS1 (0.40) | GLAPTGS1PTGS2MAPK1FABP3 | |
| SCHEMBL7100841 | 0.62 | CHRM2 (0.40) | GLAMAPK1KMOMAPTALDH1A1 | |
| SCHEMBL3151680 | 0.61 | GLA (0.53) | GLAMAPK1MAPTALDH1A1PKM | |
| SCHEMBL15391717 | 0.60 | PTGS1 (0.70) | PTGS1PTGS2MAPK1MAPTALDH1A1 | |
| SCHEMBL34464 | 0.60 | PTGS1 (0.70) | PTGS1PTGS2MAPK1MAPTALDH1A1 | |
| SCHEMBL31377154 | 0.60 | APEX1 (0.42) | GLAPTGS1MAPK1MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL25414956 | 0.58 | PTGS1 (0.68) | PTGS1PTGS2MAPK1MAPTALDH1A1 | |
| SCHEMBL28981238 | 0.58 | PTGS1 (0.68) | PTGS1PTGS2MAPK1MAPTALDH1A1 | |
| SCHEMBL6536452 | 0.58 | GLA (0.67) | GLAMAPK1MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399600-B1 | ANTIBIOTIC RESISTANT BATERIA INFECTIONS | SIMON FRASER UNIVERSITY (CA) | 2002-06-04 | — | — | US | disclosed |