Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | TYR | P14679 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.34 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1615540 | 0.78 | ALDH1A1 (0.53) | ALDH1A1ALOX15TYRLMNANR1I2 | |
| SCHEMBL5377400 | 0.77 | ALDH1A1 (0.57) | ALDH1A1ALOX15TYRLMNANR1I2 | |
| SCHEMBL5167337 | 0.75 | ALDH1A1 (0.50) | ALDH1A1ALOX15TYRLMNANR1I2 | |
| SCHEMBL28181758 | 0.74 | ALDH1A1 (0.48) | ALDH1A1ALOX15TYRLMNANR1I2 | |
| SCHEMBL74988 | 0.73 | CYP2C9 (0.52) | ALDH1A1ALOX15TYRLMNANR1I2 | |
| SCHEMBL29378822 | 0.73 | CYP2C9 (0.52) | ALDH1A1ALOX15TYRLMNANR1I2 | |
| SCHEMBL1815050 | 0.72 | ALDH1A1 (0.47) | ALDH1A1ALOX15TYRLMNANR1I2 | |
| SCHEMBL6407103 | 0.72 | ALDH1A1 (0.47) | ALDH1A1ALOX15TYRLMNANR1I2 | |
| SCHEMBL2021753 | 0.72 | ALDH1A1 (0.47) | ALDH1A1ALOX15TYRLMNANR1I2 | |
| SCHEMBL2799339 | 0.71 | TYR (0.46) | ALDH1A1ALOX15TYRLMNANR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6348591-B1 | OXIDATION AND RADIATION RESISTANCE; WATERPROOF; COATINGS, POLYMERS; STABILIZERS | CYTEC TECHNOLOGY CORP. | 2002-02-19 | — | — | US | disclosed |