Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 15/20 | 0.39 |
| ▸ | CDK4 | P11802 | 6/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7675136 | 0.82 | KMT2A (0.33) | CDK2CDK4CCNE1 | |
| SCHEMBL7693720 | 0.81 | CDK2 (0.40) | CDK2CDK4HTR6AKT1AKT2 | |
| SCHEMBL7693721 | 0.81 | CDK2 (0.40) | CDK2CDK4HTR6AKT1AKT2 | |
| SCHEMBL7676656 | 0.81 | CDK2 (0.48) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7676921 | 0.81 | AKT1 (0.45) | CDK2CDK4AKT1AKT2 | |
| SCHEMBL7676802 | 0.81 | CDK2 (0.59) | CDK2CDK4 | |
| SCHEMBL7673974 | 0.77 | CDK2 (0.60) | CDK2CDK4 | |
| SCHEMBL7683036 | 0.76 | CDK2 (0.41) | CDK2CDK4AKT1AKT2CDK1 | |
| SCHEMBL7680593 | 0.75 | CDK2 (0.42) | CDK2CDK4CDK1CCNB1CCND1 | |
| SCHEMBL7680064 | 0.74 | USP7 (0.41) | CDK2CDK4AKT1AKT2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358971-B1 | FOR INHIBITING THE GROWTH OF A PICORNAVIRUS | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |