Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 11/20 | 0.63 |
| ▸ | SCD | O00767 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003099 | 0.95 | PTGS2 (0.69) | PTGS2PTGS1PGR | |
| SCHEMBL7002074 | 0.88 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL6995425 | 0.87 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL6991394 | 0.86 | PTGS2 (0.60) | PTGS2PTGS1 | |
| SCHEMBL6996537 | 0.86 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL6995448 | 0.85 | PTGS2 (0.59) | PTGS2PTGS1 | |
| SCHEMBL7001297 | 0.85 | PTGS2 (0.50) | PTGS2PTGS1 | |
| Polmacoxib SCHEMBL29351757 | 0.85 | PTGS2 (0.55) | PTGS2PTGS1PGR | |
| Polmacoxib SCHEMBL3233093 | 0.85 | PTGS2 (0.55) | PTGS2PTGS1PGR | |
| SCHEMBL6994742 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492416-B1 | TREATING INFLAMMATION AND ASSOCIATED DISORDERS | PACIFIC CORPORATION (KR) | 2002-12-10 | — | — | US | disclosed |
| EP-1109799-A1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2001-06-27 | — | — | EP | disclosed |
| WO-2000061571-A1 | 4,5-DIARYL-3(2H)-FURANONE DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORPORATION (KR) | 2000-10-19 | — | — | WO | disclosed |