Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.71 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.71 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.58 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.57 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741064 | 0.87 | KDM4E (0.56) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL7685975 | 0.85 | RAB9A (0.59) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6512775 | 0.85 | HRH3 (0.71) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL3964905 | 0.85 | IDO1 (0.61) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL30741601 | 0.85 | IDO1 (0.61) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL8694126 | 0.84 | ATM (0.59) | ALDH1A1KDM4EHPGDHSD17B10PDGFRB | |
| SCHEMBL1564758 | 0.84 | KDM4E (0.54) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL6513821 | 0.84 | HRH3 (0.58) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL27574695 | 0.83 | IDO1 (0.60) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 | |
| SCHEMBL30994860 | 0.83 | RAB9A (1.00) | ALDH1A1KDM4EHPGDRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |
| CN-1276790-A | Carboxamidothiazole derivs., preparation, pharmaceutical composition contg. them | SANOFI SA (FR) | 2000-12-13 | — | — | CN | disclosed |