Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 14/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 14/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 14/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 14/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 14/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839514 | 0.99 | L3MBTL1 (0.43) | L3MBTL1TDP1APPCTSDBACE1 | |
| SCHEMBL19839538 | 0.99 | L3MBTL1 (0.43) | L3MBTL1TDP1APPCTSDBACE1 | |
| SCHEMBL2062804 | 0.99 | L3MBTL1 (0.43) | L3MBTL1TDP1APPCTSDBACE1 | |
| SCHEMBL13715499 | 0.99 | L3MBTL1 (0.43) | L3MBTL1TDP1APPCTSDBACE1 | |
| SCHEMBL7478239 | 0.88 | MEN1 (0.34) | L3MBTL1TDP1CHRM2CHRM4CHRM1 | |
| SCHEMBL2797900 | 0.86 | L3MBTL1 (0.36) | L3MBTL1TDP1CHRM2CHRM4 | |
| SCHEMBL2793010 | 0.86 | L3MBTL1 (0.36) | L3MBTL1TDP1CHRM2CHRM4 | |
| SCHEMBL2792896 | 0.86 | L3MBTL1 (0.36) | L3MBTL1TDP1CHRM2CHRM4 | |
| SCHEMBL7471671 | 0.85 | MAPK1 (0.33) | L3MBTL1TDP1CHRM2CHRM4 | |
| SCHEMBL8308654 | 0.85 | MAPK1 (0.33) | L3MBTL1TDP1CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6376684-B1 | CHEMICAL INTERMEDIATE FOR OXYBUTYNIN-TYPE COMPOUNDS | SEPRACOR INC. | 2002-04-23 | — | — | US | disclosed |
| EP-1127043-A1 | STEREOSELECTIVE PROCESS FOR PREPARING (CYCLO)ALKYL PHENYLGLYCOLIC ACIDS | Sepracor Inc. (US) | 2001-08-29 | — | — | EP | disclosed |
| US-6180823-B1 | CONDENSING SUBSTITUTED ACETALDEHYDE WITH ENANTIOMER OF MANDELIC ACID TO PROVIDE 5-PHENYL-1,3-DIOXOLAN-4-ONE, CONDENSING WITH CYCLOHEXANONE, DEHYDRATING PRODUCT, HYDROLYZING, REDUCING TO ALPHA-CYCLOHEXYLPHENYLGLYCOLIC ACID | SEPRACOR INC. | 2001-01-30 | — | — | US | disclosed |
| WO-2000027786-A1 | STEREOSELECTIVE PROCESS FOR PREPARING (CYCLO)ALKYL PHENYLGLYCOLIC ACIDS | SEPRACOR INC. (US) | 2000-05-18 | — | — | WO | disclosed |