Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.43 |
| ▸ | CES2 | O00748 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EP300 | Q09472 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.35 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.34 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7681914 | 1.00 | ELANE (0.43) | ELANECES2MEN1KMT2AEP300 | |
| SCHEMBL7686512 | 0.84 | MEN1 (0.41) | ELANECES2MEN1KMT2AEP300 | |
| SCHEMBL7686515 | 0.84 | MEN1 (0.41) | ELANECES2MEN1KMT2AEP300 | |
| SCHEMBL7688537 | 0.83 | CES2 (0.36) | ELANECES2MEN1KMT2AEP300 | |
| SCHEMBL30259580 | 0.83 | CES2 (0.36) | ELANECES2MEN1KMT2AEP300 | |
| SCHEMBL7688535 | 0.83 | CES2 (0.36) | ELANECES2MEN1KMT2AEP300 | |
| SCHEMBL7686176 | 0.82 | ELANE (0.46) | ELANECES2MEN1KMT2AEP300 | |
| SCHEMBL7686173 | 0.82 | ELANE (0.46) | ELANECES2MEN1KMT2AEP300 | |
| SCHEMBL30259456 | 0.73 | TSHR (0.39) | MEN1KMT2AABCB1TSHR | |
| SCHEMBL7387880 | 0.73 | TSHR (0.39) | MEN1KMT2AABCB1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021405-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2002-09-25 | — | — | EP | disclosed |
| US-6242439-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-06-05 | — | — | US | disclosed |