Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LCK | P06239 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL655194 | 0.88 | POLB (0.48) | CA12CA1CA9LMNANPSR1 | |
| SCHEMBL653538 | 0.86 | CISD2 (0.41) | CA12CA1CA9BRD9SMN1; SMN2 | |
| SCHEMBL652964 | 0.86 | CISD2 (0.41) | CA12CA1CA9LMNANPSR1 | |
| SCHEMBL28797272 | 0.86 | CYP17A1 (0.43) | CA12CA1CA9LMNANPSR1 | |
| SCHEMBL12072957 | 0.86 | LCK (0.41) | CA12CA1CA9BRD9SMN1; SMN2 | |
| SCHEMBL27828990 | 0.86 | GAA (0.46) | CA12CA1CA9LMNABRD9 | |
| SCHEMBL4568354 | 0.85 | MAPT (0.49) | CA12CA1CA9BRD9SMN1; SMN2 | |
| SCHEMBL4212736 | 0.84 | CA12 (0.41) | CA12CA1CA9BRD9LCK | |
| SCHEMBL5477161 | 0.84 | ATR (0.46) | CA12CA1CA9BRD9LCK | |
| SCHEMBL14386620 | 0.84 | SMN1; SMN2 (0.40) | CA12CA1CA9LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380230-B1 | FOR THERAPY OF DYSKINESIA, OBESITY, IRRITABLE BOWEL SYNDROME, DISEASES WHOSE TREATMENT REQUIRES STIMULATION OF THE CHOLECYSTOKININ CCK-A RECEPTORS | SANOFI-SYNTHELABO (FR) | 2002-04-30 | — | — | US | disclosed |