Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 18/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7679269 | 0.86 | LSS (0.41) | LSSMEN1KMT2A | |
| SCHEMBL7679251 | 0.85 | LSS (0.60) | LSSMEN1KMT2A | |
| SCHEMBL7767798 | 0.85 | LSS (0.60) | LSSMEN1KMT2A | |
| SCHEMBL7679262 | 0.85 | LSS (0.60) | LSSMEN1KMT2A | |
| SCHEMBL7679255 | 0.85 | LSS (0.60) | LSSMEN1KMT2A | |
| Fumaric Acid SCHEMBL7682141 | 0.83 | LSS (0.56) | LSSMEN1KMT2A | |
| Fumaric Acid SCHEMBL7682131 | 0.83 | LSS (0.56) | LSSMEN1KMT2A | |
| SCHEMBL7677286 | 0.78 | LSS (0.73) | LSSPOLBMAPT | |
| SCHEMBL7677292 | 0.78 | LSS (0.73) | LSSPOLBMAPT | |
| SCHEMBL3684952 | 0.77 | LSS (0.62) | LSSNPC1MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6441177-B1 | Tertiary amines | HOFFMANN-LA ROCHE INC. | 2002-08-27 | — | — | US | disclosed |
| US-6034275-A | FUGICIDES; ATICHOLESTEROL AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-03-07 | — | — | US | disclosed |