Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | THRB | P10828 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | GALK1 | P51570 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682169 | 1.00 | MEN1 (0.64) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL5469970 | 0.81 | MEN1 (0.83) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL5469976 | 0.81 | MEN1 (0.83) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL28967915 | 0.76 | MEN1 (0.71) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL28967912 | 0.76 | MEN1 (0.71) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7685215 | 0.76 | KMT2A (0.64) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL7685217 | 0.76 | KMT2A (0.64) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL3134918 | 0.75 | KMT2A (0.74) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL3134925 | 0.75 | KMT2A (0.74) | MEN1KMT2AMAPTALDH1A1GAA | |
| SCHEMBL5462957 | 0.74 | MEN1 (0.53) | MEN1KMT2AMAPTALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410533-B1 | THERAPY FOR BACTERIA INFECTIONS | GENZYME CORPORATION | 2002-06-25 | — | — | US | disclosed |