Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | NPC1 | O15118 | 2/20 | 0.64 |
| ▸ | RAB9A | P51151 | 2/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 2/20 | 0.46 |
| ▸ | GALK1 | P51570 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7685215 | 1.00 | KMT2A (0.64) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL9727216 | 0.88 | KMT2A (0.75) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL9524422 | 0.88 | KMT2A (0.75) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL9651820 | 0.82 | KMT2A (0.71) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL9651814 | 0.82 | KMT2A (0.71) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL9525748 | 0.79 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL9524411 | 0.78 | KMT2A (0.66) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL10422268 | 0.78 | KMT2A (0.66) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL9653587 | 0.77 | KMT2A (0.50) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL15269833 | 0.77 | KMT2A (0.64) | KMT2AMEN1ALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410533-B1 | THERAPY FOR BACTERIA INFECTIONS | GENZYME CORPORATION | 2002-06-25 | — | — | US | disclosed |