Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3217573 | 1.00 | CYP2D6 (0.48) | CYP2D6CYP3A4LMNANPC1SMN1; SMN2 | |
| SCHEMBL27891191 | 0.98 | CYP2D6 (0.50) | CYP2D6CYP3A4LMNANPC1SMN1; SMN2 | |
| SCHEMBL4495041 | 0.91 | CYP2D6 (0.52) | CYP2D6CYP3A4LMNANPC1SMN1; SMN2 | |
| SCHEMBL9804775 | 0.89 | CYP2D6 (0.66) | CYP2D6CYP3A4LMNANPC1SMN1; SMN2 | |
| SCHEMBL1097898 | 0.85 | ALDH1A1 (0.60) | CYP2D6CYP3A4LMNANPC1SMN1; SMN2 | |
| SCHEMBL9804722 | 0.84 | KDM4E (0.50) | CYP2D6CYP3A4NPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL9804676 | 0.84 | KDM4E (0.50) | CYP2D6CYP3A4NPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL19621751 | 0.84 | PRMT1 (0.54) | CYP2D6ALDH1A1RECQLKCNA3TSHR | |
| SCHEMBL10731573 | 0.82 | KCNA3 (0.55) | CYP2D6ALDH1A1RECQLKCNA3L3MBTL1 | |
| SCHEMBL12743776 | 0.82 | CYP2D6 (0.59) | CYP2D6CYP3A4LMNANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359056-B1 | CAPABLE OF EXTENDED PRESS RUN LENGTH WHICH DOES NOT REQUIRE CHEMICAL DEVELOPMENT | KODAK POLYCHROME GRAPHICS LLC | 2002-03-19 | — | — | US | disclosed |
| EP-1120248-A2 | Printing plate and method for its preparation | Kodak Polychrome Graphics Company Ltd. (US) | 2001-08-01 | — | — | EP | disclosed |