SCHEMBL7682205

SCHEMBL7682205

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nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.31
HTT P42858 1/20 0.30
SLC1A3 P43003 1/20 0.30
SLC1A2 P43004 1/20 0.30
SLC1A1 P43005 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28225324 1.00 TSHR (0.31) TSHRHTTSLC1A3SLC1A2SLC1A1
SCHEMBL3415836 0.79 TSHR (0.33) TSHRHTT
SCHEMBL11588813 0.74
SCHEMBL1336756 0.73 TSHR (0.50) TSHRHTT
SCHEMBL571478 0.73 TSHR (0.50) TSHRHTT
SCHEMBL8636434 0.73 TSHR (0.50) TSHRHTT
SCHEMBL11669820 0.73 TSHR (0.36) TSHRHTT
SCHEMBL1338978 0.73 TSHR (0.50) TSHRHTT
Ammonia Solution, Strong SCHEMBL28192237 0.72 SLC7A5 (0.36) TSHRSLC1A3SLC1A2SLC1A1
SCHEMBL11456317 0.72 TSHR (0.50) TSHRSLC1A3SLC1A2SLC1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020052295-A1 Diacyl derivatives of propylene diamine having herbicidal activity MONSANTO TECHNOLOGY LLC 2002-05-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020052295-A1 Diacyl derivatives of propylene diamine having herbicidal activity DDT, SAT1, AOC1 TSHR 493/4885HTT 2364/4885SLC1A3 1294/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.