Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 12/20 | 0.41 |
| ▸ | CASP3 | P42574 | 5/20 | 0.37 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682125 | 0.92 | CASP1 (0.39) | CASP1CASP3CASP6CASP8ALDH1A1 | |
| SCHEMBL7681919 | 0.85 | CASP1 (0.38) | CASP1CASP3ALDH1A1 | |
| SCHEMBL7681935 | 0.85 | CASP1 (0.41) | CASP1CASP3CASP6CASP8 | |
| SCHEMBL7679421 | 0.85 | CASP1 (0.43) | CASP1CASP3ALDH1A1 | |
| SCHEMBL7676849 | 0.85 | CASP1 (0.38) | CASP1CASP3ALDH1A1GHSR | |
| SCHEMBL7675762 | 0.83 | CASP1 (0.37) | CASP1CASP3CASP6CASP8ALDH1A1 | |
| SCHEMBL7686197 | 0.83 | CASP1 (0.37) | CASP1CASP3ALDH1A1GHSR | |
| SCHEMBL7680995 | 0.83 | CASP1 (0.53) | CASP1CASP3 | |
| SCHEMBL7683990 | 0.83 | CASP1 (0.40) | CASP1CASP3 | |
| SCHEMBL7677095 | 0.82 | CASP1 (0.36) | CASP1CASP3GHSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | claimed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | claimed |
| US-6376484-B1 | FOR PREVENTION AND/OR TREATMENT OF VARIOUS KINDS OF INFLAMMATORY DISEASE | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-04-23 | — | — | US | disclosed |
| US-6136834-A | TETRAZOLE PEPTIDES | ONO PHARMACEUTICAL CO., LTD. (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-0900791-A1 | TETRAZOLE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 1999-03-10 | — | — | EP | disclosed |