Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.33 |
| ▸ | ITGA5 | P08648 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.30 |
| ▸ | ITGAV | P06756 | 1/20 | 0.30 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682384 | 1.00 | POLB (0.39) | POLBRIPK1ITGB1ITGA5MAPT | |
| SCHEMBL10642382 | 0.72 | L3MBTL1 (0.41) | POLB | |
| SCHEMBL28908821 | 0.71 | MEN1 (0.40) | — | |
| SCHEMBL20471528 | 0.67 | AR (0.34) | POLBRIPK1ITGB1ITGA5MAPT | |
| SCHEMBL3336957 | 0.67 | AR (0.34) | POLBRIPK1ITGB1ITGA5MAPT | |
| SCHEMBL22978565 | 0.67 | AR (0.34) | POLBRIPK1ITGB1ITGA5MAPT | |
| SCHEMBL3607555 | 0.67 | AR (0.34) | POLBRIPK1ITGB1ITGA5MAPT | |
| SCHEMBL20835810 | 0.66 | ACE (0.33) | — | |
| SCHEMBL25489357 | 0.66 | CHRM2 (0.38) | POLBMAPT | |
| SCHEMBL28898088 | 0.64 | ACE (0.38) | POLBRIPK1ITGB1ITGA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021405-B1 | AZETIDINONE DERIVATIVES FOR THE TREATMENT OF HCMV INFECTIONS | BOEHRINGER INGELHEIM CA LTD (CA) | 2002-09-25 | — | — | EP | disclosed |
| US-6242439-B1 | Azetidinone derivatives for the treatment of HCMV infections | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2001-06-05 | — | — | US | disclosed |