SCHEMBL76824

SCHEMBL76824

O=C(O)N1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27198163 0.97
SCHEMBL1151783 0.97 ALDH1A1 (0.58)
SCHEMBL21291787 0.97 ALDH1A1 (0.58)
SCHEMBL336899 0.97
SCHEMBL6704420 0.97 ALDH1A1 (0.58)
SCHEMBL9537676 0.97 ALDH1A1 (0.58)
Ammonia Solution, Strong SCHEMBL6056846 0.97
Bromide SCHEMBL1732225 0.97
SCHEMBL64790 0.97
Hydrochloric Acid SCHEMBL3548414 0.97

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4340 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026090333-A1 COMBINATION USING A KRAS G12D INHIBITOR AND CHEMOTHERAPY COMBINATIONS AS WELL AS THEIR USE IN THE TREATMENT OF CANCER INCYTE CORPORATION (US) 2026-04-30 WO claimed
EP-3924058-B1 5-ALKYL PYRROLIDINE OREXIN RECEPTOR AGONISTS MERCK SHARP & DOHME LLC (US) 2026-01-07 EP claimed
EP-4301736-B1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2025-10-08 EP claimed
WO-2025080592-A1 COMBINATION COMPRISING A KRAS G12D INHIBITOR AND AN EGFR INHIBITOR FOR USE IN THE TREATMENT OF CANCER INCYTE CORPORATION (US) 2025-04-17 WO claimed
WO-2025080593-A1 COMBINATION THERAPY USING A KRAS G12D INHIBITOR AND PD-1 INHIBITOR OR PD-L1 INHIBITOR INCYTE CORPORATION (US) 2025-04-17 WO claimed
EP-4251620-B1 AMINO QUINAZOLINE DERIVATIVES AS P2X3 INHIBITORS CHIESI FARM SPA (IT) 2025-04-16 EP claimed
EP-4514799-A2 CERTAIN CHEMICAL ENTITIES, COMPOSITIONS, AND METHODS MRJA Therapeutics, Inc. (US) 2025-03-05 EP claimed
EP-4219460-B1 TRANSGLUTAMINASE 2 (TG2) INHIBITORS SITARI PHARMA INC (US) 2025-02-26 EP claimed
WO-2024259191-A2 METHOD AND COMPOSITIONS FOR TREATING SKIN DISORDERS PHOENIX BIOTECHNOLOGY, INC. (US) 2024-12-19 WO claimed
US-20240415819-A1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS QLi5 Therapeutics AG (DE) 2024-12-19 US claimed
US-4766133-A ANTIULCER AGENTS HOFFMAN-LA ROCHE INC. (US) 1988-08-23 US claimed
US-4727060-A HYPOTENSIVE AGENTS CIBA-GEIGY CORPORATION (US) 1988-02-23 US claimed
EP-0214479-A2 Benzimidazol-2-ylpyridinium compounds F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) 1987-03-18 EP claimed
EP-0187956-A2 Pharmaceutical composition for the treatment of defects of the gastrointestinal mucous membrane BOEHRINGER INGELHEIM KG (DE) 1986-07-23 EP claimed
EP-0184550-A2 5-Amino-4-hydroxy valeryl amide derivatives CIBA-GEIGY AG (CH) 1986-06-11 EP claimed
EP-0078099-B1 SUBSTITUTED PHENYL (THIONO)CARBAMATES, HERBICIDAL COMPOSITIONS CONTAINING THE SAME AS ACIVE INGREDIENT AND METHOD OF CONTROLLING WEEDS KURARAY CO., LTD. (JP) 1985-11-27 EP claimed
EP-0143746-A2 5-Amino 4-hydroxy-valeryl-substituted derivatives CIBA-GEIGY AG (CH) 1985-06-05 EP claimed
EP-0065372-A1 Substituted phenyl (thiono)carbamates, herbicidal compositions containing the same as active ingredient and method of controlling weeds KURARAY CO., LTD. (JP) 1982-11-24 EP claimed
US-4013445-A 1-(Bis-trifluoromethylphenyl)-2-oxo-pyrrolidine-4-carboxylic acid derivatives, their production and their use as plant-growth regulators and herbicides CIBA-GEIGY CORPORATION (US) 1977-03-22 US claimed
US-3962224-A CHEMICAL INTERMEDIATES FOR ANTIBIOTICS MERCK & CO., INC. (US) 1976-06-08 US claimed